| Professor Andrew Scholey Monash and Swinburne Universities Melbourne Australia Email: andrew@scholeylab.com (or click icon top right) |
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My research... |
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I
am interested in the way in which substances - 'nutra' interventions
(nutrition, nutrients, nutraceuticals), caffeine, drugs, alcohol
and alcohol hangover change the human brain, physiology and behaviour.
I have led over 100 studies of into the human biobehavioural effects of natural products, and their neurocognition-enhancing and anti-stress/anxiolytic properties including numerous first-into-human neurocognitive clinical trials. I work closely with industry to translate research into evidence-based interventions for optimum brain health.
Broadly my research can be divided into the following themes:
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'Nutra' interventions for brain health |
Alcohol and drugs |
Alcohol Hangover |
Physiological response to mental effort |
Glucose and oxygen effects on cognitive performance |
| This research examines the potential for nutritional interventions, including diet, isolated nutrients and botanical extracts to improve mood and cognitive function. My research has shown that certain classes of bioactive nutrients appear to improve mood and cognition acutely. Others may protect against age-associated cognitive decline. | This stream of research examines the acute and chronic effects of recreational drugs (including MDMA/Ecstasy and alcohol). My research suggests that alcohol intoxication "uncalibrates" people so error monitoring and feedback is impaired. Other recreational drugs also have long-term negative behavioural effects. | This research examines the cognitive, mood and physiological effects of alcohol hangover - an area which is surprisingly under- researched. Our research in this area suggests that hangover is associated with negative mood and cognitive deficits which suggest reduced cognitive resources. These results have profound effects for everyday behaviours such as driving. | My research suggests that there is a correspondence between the subjective experience of cognitive 'strain' and the utilisation of central resources. At the same time, during mental effort a number of physiological responses serve to facilitate provision of energetic resources. Some cognition enhancing interventions have similar effects. | The brain is highly metabolically active, utilising a large percentage of the body's glucose and oxygen. Its function is therefore highly sensitive to fluctuations in the levels of these substances. This research examined the cognitive enhancing effects of of glucose and oxygen administration. The effects seem to be most evident under conditions of high mental effort. |
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